📄 Category

cardiovascular medicine

131 papers

Cardiovascular medicine focuses on the heart and blood vessels, exploring how to prevent, diagnose, and treat conditions that affect our circulation. This vital field ranges from understanding high blood pressure and heart failure to investigating the latest breakthroughs in surgical techniques and lifestyle interventions. Because these discoveries directly impact public health, staying informed about emerging research is more important than ever for both specialists and curious readers.

At Gist.Science, we process every new preprint in this category as it appears on medRxiv, ensuring you have immediate access to the latest findings before they undergo formal peer review. For each study, we provide both a plain-language explanation to clarify the core concepts and a detailed technical summary for those seeking deeper scientific context. Below are the latest papers in cardiovascular medicine, organized to help you navigate the most recent developments shaping the future of heart health.

📄 cardiovascular medicine

Title: Prevalence and Determinants of Hypertension Among People Living with HIV on Antiretroviral Therapy: A Cross-Sectional Study at Mwananyamala Hospital, Tanzania.

This cross-sectional study at Mwananyamala Hospital in Tanzania reveals a 32.8% prevalence of hypertension among people living with HIV on antiretroviral therapy, identifying older age, cigarette smoking, and longer duration since HIV diagnosis as significant risk factors while highlighting the need for integrated screening and education to address this growing comorbidity.

MORICE, M., Mgumia, J.2026-02-26
📄 cardiovascular medicine

SOLO study: A single-pill combination strategy in general practice to optimize blood pressure control in a multi-ethnic community

The SOLO study demonstrates that promoting single-pill combination therapy through a targeted care improvement project in a disadvantaged, multi-ethnic primary care setting significantly increased treatment initiation and improved blood pressure control compared to usual care.

Harskamp, R., Naaktgeboren, W. R., Strijp, J., Smits, S., Himmelreich, J. C. L.2026-02-26
📄 cardiovascular medicine

Explainable advanced electrocardiography predicts coronary artery disease on coronary computed tomography angiography

This study demonstrates that an explainable advanced electrocardiography (A-ECG) model, derived from standard 12-lead ECG features, provides modest but externally reproducible discrimination for detecting coronary artery disease on CT angiography and independently predicts future cardiovascular events in a large population cohort.

Rajamohan, M., Loewenstein, D. E., Maanja, M., Al-Falahi, Z., Kuhasri, A., Yang, K. X., Cheepvasarach, C., Lindow, T., S (…)2026-02-24
📄 cardiovascular medicine

Triglyceride-rich lipoproteins, low-density lipoproteins, and risk of abdominal aortic aneurysm

This study utilizes Mendelian randomization to demonstrate that triglyceride-rich lipoproteins are at least three times more aneurysmogenic than low-density lipoproteins on a per-particle basis, suggesting that therapeutic strategies targeting TRL pathways, particularly APOC3 and LPL, should be prioritized for abdominal aortic aneurysm prevention.

Yuan, S., Bjornson, E., Shakt, G., Dinatale, T., Lynch, J., Temel, R. E., Lu, H. S., Daugherty, A., Chang, K.-M., Tsao (…)2026-02-24
📄 cardiovascular medicine

Multimodal Deep Learning for Structural Heart Disease Prediction from ECG and Clinical Data

This research demonstrates that a Temporal Convolutional Network (TCN) architecture outperforms other deep learning models in predicting structural heart disease from ECG and clinical data, offering statistically significant, stable, and computationally efficient performance suitable for fair healthcare applications.

Ajadi, N. A., Afolabi, S. O., Adenekan, I. O., Jimoh, A. O., Ajayi, A. O., Adeniran, T. A., Adepoju, G. D., Hassan, N. F (…)2026-02-24
📄 cardiovascular medicine

Population-Wide Assessment of Heart Rhythm and Physical Activity from 14-Day Recordings: The UK Biobank Cardiac Monitoring Study

The UK Biobank Cardiac Monitoring Study utilized 14-day patch-based ECG and accelerometer data from 27,658 participants to characterize population-wide heart rhythms and physical activity, revealing significant rates of undiagnosed atrial fibrillation and distinct circadian patterns of arrhythmias linked to activity levels.

van Duijvenboden, S., El-Medany, A., Aggour, H., Orini, M., Bai, W., Gallacher, J. E., Hopewell, J. C., Bell, S., Ng, F. (…)2026-02-24
📄 cardiovascular medicine

Spiral Septal Morphology Distinguishes Arrhythmic from Idiopathic DCM and Links to Prognosis

This study demonstrates that specific left ventricular morphological features, particularly the absence of a spiral septal pattern and a more conical shape, can effectively distinguish arrhythmic dilated cardiomyopathy from idiopathic cases and predict adverse arrhythmic outcomes beyond traditional markers like mass, function, or late gadolinium enhancement.

Asher, C., Balaban, G., Musicha, C., Razavi, R. S., Carr-White, G. S., Lamata, P.2026-02-19
📄 cardiovascular medicine

Electrocardiographic Digital Biomarkers in Asymptomatic Schoolchildren with Rheumatic Heart Disease

This study demonstrates that specific electrocardiographic parameters, including prolonged PR intervals, increased P-wave dispersion, and a reduced P-wave to PR interval ratio, serve as significant non-invasive digital biomarkers for screening asymptomatic rheumatic heart disease in schoolchildren, offering a viable strategy for early detection in resource-limited settings.

Chuma, A. T., Voigt, J.-U., Youssef, A. S., Asmare, M. H., Wang, C., Varon, C., Willems, R., Kassie, D. M., Vanrumste, B (…)2026-02-18
📄 cardiovascular medicine

Acute myocardial infarction releases more troponin per unit of late gadolinium enhancement mass compared to acute myocarditis

This study demonstrates that while peak high-sensitivity cardiac troponin correlates with late gadolinium enhancement extent in both acute myocardial infarction and acute myocarditis, the former releases significantly more troponin per unit of myocardial injury mass, indicating that troponin-based estimates of injury size are not directly interchangeable between these two conditions.

Rajamohan, M., Dind, A., Ugander, M., Figtree, G. A., Kozor, R.2026-02-18